CAS 50650-59-4 | 2-Hydroxy-4-(trifluoromethyl)pyridine

Molecular Formula: C6H4F3NO
Molecular Weight: 163.1
EINECS: 610-554-0
Purity: 97% Min.
Package: 1 g / 5 g / 25 g / 100 g / 1 kg
Worldwide Delivery

Application

Introduction
2-Hydroxy-4-(trifluoromethyl)pyridine is a fuorine-containing pyridine intermediate.

Specification of CAS 50650-59-4 | 2-Hydroxy-4-(trifluoromethyl)pyridine

ITEMS

SPECIFICATION

Melting point

161-165 °C (lit.)

storage temp.

Inert atmosphere,Room Temperature

solubility

Soluble in methanol.

density

1.398 g/cm3

Boiling point

221.2 °C

pka

10.76

CAS DataBase Reference

50650-59-4(CAS DataBase Reference)

Synthesis of CAS 50650-59-4 | 2-Hydroxy-4-(trifluoromethyl)pyridine

CAS 50650-59-4 | 2-Hydroxy-4-(trifluoromethyl)pyridine

Conditions:

With nickel(II) sulfate hexahydrate; 4,4'-Dimethoxy-2,2'-bipyridin; 8,9-bis((R)-2-acetoxypropyl)-7,10-dimethoxyperyleno[1,12-def][1,3]dioxepine-5,6,11,12-tetrayl tetraacetate; 18O-labeled water; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide; acetonitrile at 20℃; for 48h; Schlenk technique; Irradiation; Inert atmosphere;

Reference:

Guo, Baodang; Huang, Shuping; Li, Jia; Li, Min; Liu, Xuanzhong; Rao, Yijian; Wu, Yawen; Yin, Huimin; Yuan, Zhenbo; Zhang, Yan

[Journal of Catalysis, 2021, vol. 399, p. 111 – 120]

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