CAS 775304-57-9 | Ataluren (PTC124)

Molecular Formula: C15H9FN2O3
Molecular Weight: 284.24
Purity: 97% Min.
Package: 100 mg / 250 mg / 1 g / 5 g
Worldwide Delivery

Application

Introduction
Ataluren (PTC124) selectively induces ribosome transcriptional read-through, but does not affect normal stop codons. EC5Chemicalbook0 is 0.1 μM in HEK293 cells, which can treat familial hereditary diseases caused by nonsensemutations (such as CF caused by nonsense mutations in CFTR)

Specification of CAS 775304-57-9 | Ataluren (PTC124)

ITEMS

SPECIFICATION

CAS DataBase Reference

775304-57-9

Boiling point

503.7 °C

Form

White to off-white solid.

pka

3.58

Density

1.379

Synthesis of CAS 775304-57-9 | Ataluren (PTC124)

CAS 775304-57-9 | Ataluren (PTC124)

Conditions

With basic cobalt(II) carbonate; sodium bromide In acetic acid at 95℃; for 11h; Green chemistry;

Reference

Krasouskaya; Danilova; Baikov; Kolobov; Kofanov

[Russian Chemical Bulletin, 2015, vol. 64, # 1, p. 142 – 145]

[Izv. Akad. Nauk, Ser. Khim., 2015, # 1, p. 142 – 145,4]

Hot Tags: cas 775304-57-9 | ataluren (ptc124), price, quotation, discount, in stock, for sale, MOF COF Ligands, Photocatalysts, Phenylbis 2 4 6 trimethylbenzoyl phosphine oxide, Fluorene, Aggregation Induced Emission, Catalyst Ligands

CAS:1195768-06-9 | Dabrafenib Mesylate

CAS:486460-00-8 Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid

send us a message

    Home Tel Mail Inquiry