CAS 83857-96-9 | 2-Butyl-4-chloro-5-formylimidazole

Molecular Formula: C8H11ClN2O
Molecular Weight: 186.64
EINECS: 410-260-0
Purity: 97% Min.
Package: 1 g / 5 g / 25 g / 100 g / 1 kg / 25 kg
Worldwide Delivery

Application

Introduction
2-Butyl-4-chloro-5-formylimidazole is used as an intermediate of antihypertensive drug losartan.

Specification of CAS 83857-96-9 | 2-Butyl-4-chloro-5-formylimidazole

ITEMS

SPECIFICATION

Melting point

97-100 °C(lit.)

InChIKey

JLVIHQCWASNXCK-UHFFFAOYSA-N

storage temp.

Inert atmosphere,2-8°C

solubility

slightly soluble

form

neat

Water Solubility

slightly soluble

density

1.240

Boiling point

384.1 °C

pka

8.87

EPA Substance Registry System

2-Butyl-5-chloroimidazole-4-carbaldehyde (83857-96-9)

CAS DataBase Reference

83857-96-9(CAS DataBase Reference)

Synthesis of CAS 83857-96-9 | 2-Butyl-4-chloro-5-formylimidazole

CAS 83857-96-9 | 2-Butyl-4-chloro-5-formylimidazole

Conditions

Stage #1: (1-iminopentyl)glycine tert-butyl ester With trifluoroacetic acid In 1,2-dichloro-ethane at 20℃; for 24h; Large scale;

Stage #2: With trichlorophosphate In toluene at 80℃; for 2h; Large scale; Stage #3: N,N-dimethyl-formamide In toluene at 105℃; for 7h; Temperature; Large scale;

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