CAS:23828-92-4 | Ambroxol Hydrochloride

Molecular Formula:C13H18Br2N2O•HCl 
Molecular Weight:414.56g/mol
Purity:98%
Package:5g/10g/25g/50g/bulk package
Transportation: FeDex/DHL/Ocean shipping /Clients requirement

Application

Applications

 

Ambroxol hydrochloride(CAS:23828-92-4) is a small molecule expectorant and mucolytic agent with antioxidant and antiinflammatory effects. Ambroxol stimulates the secretion of surfactant which decreases mucus adhesion to the bronchial lining and produces expectorant effects. The antioxidant effects of Ambroxol are well demonstrated, where lipid peroxidation initiated by t-butyl hydroperoxide or doxorubicin is suppressed in the presence Ambroxol, and scavenging of hydroxyl radicals and cellular superoxide radical anions is also observed. Ambroxol produces antiinflammatory effects by blocking the expression of proinflammatory messengers, inhibiting the release of histamine from mast cells and the generation of cytokines and interleukins. Ambroxol hydrochloride is an inhibitor of Sodium Channel Protein.

 

Specification

ITEMS

SPECIFICATION

IUPAC Name

4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol;hydrochloride

MDL No

MFCD00078932

Boiling Point

468.6ºC at 760 mmHg

Melting Point

>235°C (dec.)

Flash Point

237.2ºC

PSA

58.28

LogP

4.96

Appearance

White to off-white (Solid)

Solubility

Soluble in methanol, water (~5 mg/ml), ethanol (~5 mg/ml), and DMSO (50 mM). Insoluble in ether

Storage condition

2-8°C, sealed storage, away from moisture

InChI

InChI=1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H

InChIKey

QNVKOSLOVOTXKF-UHFFFAOYSA-N

CAS:23828-92-4 | Ambroxol Hydrochloride

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